Zeku County, under the jurisdiction of Huangnan Tibetan Autonomous Prefecture of Qinghai Province, is located in the southeast of Qinghai Province. In the south of Huangnan Tibetan Autonomous Prefecture, it is adjacent to Xiahe County of Gansu Province in the east, Mongolian Autonomous County of Henan Province in the south, Tongde County of Qinghai Province in the west, and Tongren in the northeast. The total area is 6550 square kilometers. As of midnight on November 1, 2020, the permanent population of Zeku County was 75,659. As of October 31, 2021, Zeku County has jurisdiction over 4 towns and 3 townships. County people's government in Zequ Town happiness Road 163.

In the 18th year of the Republic of China (1929), Qinghai province, from the Xunhua department disintegrated Tongren County, Zeku area belongs to Tongren County jurisdiction. In December 1953, Tongren County analyzed the fifth, sixth, seventh district set up Zeku County. On April 21, 2020, the People's Government of Qinghai Province issued an announcement, agreeing to remove Zeku County from the poverty-stricken county list.
In 2020, the GDP of Zeku County reached 2.027 billion yuan, an increase of 3.1 percent year-on-year. Among them, the primary industry was 1.106 billion yuan, up 4.9% year on year; The secondary industry was 241 million yuan, down 1.2% year-on-year; The tertiary industry reached 680 million yuan, up 2.3 percent year on year.