Zhenning Buyi and Miao Autonomous County, located between the watershed of the Pearl River system and the Yangtze River system in southwest Guizhou Province, belongs to Anshun City. It is located at 105°35 'to 106°1' east longitude and 25°25 'to 26°11' north latitude. The east is adjacent to Xixiu District of Anshun City and Ziyun Miao Buyi Autonomous County; It faces Beipan River in the south, Wangmo and Zhenfeng counties of Qianxinan Autonomous Prefecture across the river, and Guanling Buyi and Miao Autonomous County in the west. North and Puding County, Liuzhi Special Zone adjacent. The seat of the county people's government is Zhenning. County land area of 1717.29 square kilometers. Zhenning is inhabited for a long time by 23 ethnic groups such as Han nationality, Buyi nationality, Miao nationality and Gelao nationality. Jurisdiction over 5 streets, 8 towns, 3 townships, 4 communities. According to the seventh census, as of midnight on November 1, 2020, the permanent population of Buyi and Miao Autonomous County in Zhenning was 299,696.

In 2013, the total output value of agriculture, forestry, animal husbandry and fishery in Buyi and Miao Autonomous County of Zhenning reached 1,03549 million yuan. Huangguoshu Waterfall in Zhenning is the largest waterfall in China and one of the most famous waterfalls in the world. On September 25, 2018, it was awarded the honorary title of "2018 E-commerce into Rural Comprehensive Demonstration County" by the Ministry of Commerce. On April 24, 2019, the People's Government of Guizhou Province officially approved Zhenning Buyi and Miao Autonomous County to be removed from the poverty-stricken county list. In 2020, the GDP of Buyi and Miao Autonomous County in Zhenning reached 11.613 billion yuan, an increase of 3.9% over the previous year.