He County is located in the central area of the Yangtze River Delta, the eastern part of Anhui Province, and the north bank of the lower reaches of the Yangtze River. It faces Nanjing, Ma 'anshan and Wuhu across the river. The border is long from north to south, narrow from east to west, and the terrain slopes from northwest to southeast. In the south and along the Yangtze River, the terrain is relatively flat. It is the alluvial plain of the Yangtze River, crisscrosed by ditches, rivers, ports and branches, and dotted with reservoirs and pits. It belongs to the North subtropical humid monsoon climate. It covers an area of 1319 square kilometers and has jurisdiction over 9 towns. As of 2021, He County has a registered population of 536,700.

He County is a famous historical and cultural city, which has a history of more than 2,200 years. There are historical and cultural sites such as "Hexian Ape Man", Bawang Temple, Tianmen Mountain, Shanzhai Room, etc. The poet Zhang Ji in Tang Dynasty, the Song Dynasty Song Haodu Mo, the Ming Dynasty poet Dai Zhong, the Qing Dynasty painter Dai Benxiao and so on are all from Hezhou. Hexian County has nurtured the contemporary grass holy forest and raised Xu Haifeng, the first gold medal winner of China's Olympic Games. The Yangtze River, a golden waterway, flows through 55 kilometers of He County. Zhengpu Port is a 10,000-ton deep water port approved by the National Development and Reform Commission after Shanghai and Nanjing. In November 2021, it will be selected into the public list of "Four Good Rural Road" national demonstration county.

In 2021, the GDP of Hexian County reached 31.75 billion yuan (including Zhengpu Port New Area), an increase of 12.2% at comparable prices.